Single-use Bioprocessing Market Size, Share, Growth, and Industry Analysis, By Types (PH Sensor, Valve, Bench Top Control System, Spectroscopy), By Applications Covered (Biotechnology Industry, Pharmaceutical Industry, Academic Research), Regional Insights and Forecast to 2033

Single-use Bioprocessing Market size

The Single-use Bioprocessing Market was valued at USD 4,172.4 million in 2024 and is expected to reach USD 4,593.81 million in 2025, growing to USD 10,221.81 million by 2033, with a CAGR of 10.1% during the forecast period [2025-2033].

The US Single-use Bioprocessing Market is witnessing significant growth due to the increasing demand for biopharmaceuticals, advancements in technology, and expanding applications in biotechnology and pharmaceutical industries, contributing to a substantial market share in North America.

The Single-use Bioprocessing market is projected to grow rapidly due to its cost-effective and scalable benefits in biomanufacturing. Key components like pH sensors, valves, bench-top control systems, and spectroscopy devices contribute to a market expected to expand by around 15% over the forecast period. The increased demand for biologics and biosimilars is expected to drive significant adoption of these systems, accounting for up to 60% of the market's growth.

Market Trends in Single-use Bioprocessing

The adoption of single-use bioprocessing systems is anticipated to grow by 12% annually, driven by the need for flexibility and cost savings in biotechnology and pharmaceutical production. pH sensors and spectroscopy systems are expected to grow by 18% as they ensure quality control in biologic manufacturing. Bench-top control systems are likely to account for 20% of market share due to their relevance in academic and research applications. The transition from stainless-steel systems to single-use options is expected to reduce operational costs by up to 30%, enhancing market adoption.

Market Dynamics

The dynamics of the Single-use Bioprocessing market are influenced by a combination of factors, including growing demand for biologics, technological advancements, and the need for cost-effective solutions. pH sensors, valves, bench-top control systems, and spectroscopy devices are integral to driving process efficiencies in biotechnology, pharmaceuticals, and academic research. The market is expected to expand as companies continue to shift towards disposable technologies, offering flexibility and reduced risk of cross-contamination. Moreover, the demand for biologics and biosimilars continues to rise, further driving the adoption of single-use systems. These systems cater to various applications such as large-scale production in pharmaceuticals and R&D in academic institutions.

Drivers of Market Growth

"Increasing demand for biologics and biosimilars"

The growth in the biopharmaceutical industry, particularly in biologics and biosimilars, is driving market expansion. The demand for safer, more efficient, and cost-effective production methods is expected to surge by over 25%, fueling the adoption of single-use bioprocessing systems. pH sensors, valves, and spectroscopy technologies help monitor production quality, ensuring compliance with regulatory standards. Additionally, single-use systems offer flexibility, which makes them highly attractive for large-scale and continuous production processes in the biotechnology sector, enabling greater yields without incurring high capital investment costs.

Market Restraints

"High cost of single-use equipment"

One major restraint to the growth of the Single-use Bioprocessing market is the initial high cost of equipment. While single-use systems offer long-term cost savings due to lower maintenance and cleaning requirements, the initial capital investment for equipment like bench-top control systems or spectroscopy devices can be up to 20-30% higher than traditional systems. Smaller biotech firms and academic institutions may find it challenging to justify these upfront costs despite long-term benefits, limiting adoption in these sectors. Furthermore, the limited lifespan of single-use systems can contribute to higher long-term expenditures compared to stainless-steel systems.

Market Opportunities

"Expansion of personalized medicine"

The rise of personalized medicine offers significant growth opportunities for the Single-use Bioprocessing market. With the increasing need for custom-tailored therapies, especially in oncology and immunology, the demand for flexible, scalable production systems is expected to increase by approximately 15%. Single-use systems are ideal for these applications as they allow rapid adjustments in production and easily accommodate smaller batches of biologics and cell therapies. The growing trend toward gene therapies and cell-based treatments will further increase the use of single-use technologies, particularly in the biotechnology and pharmaceutical industries.

Market Challenges

"Supply chain disruptions and material shortages"

One of the challenges facing the Single-use Bioprocessing market is the vulnerability of the supply chain, particularly concerning the availability of high-quality raw materials. Recent global disruptions have caused material shortages and delays in the production of critical components like pH sensors and valves. Supply chain challenges have the potential to delay production timelines for manufacturers and research organizations, impacting market growth. Moreover, the reliance on disposable components leads to environmental concerns regarding waste management, which could hinder market adoption in regions with stringent environmental regulations.

Segmentation Analysis Single-use Bioprocessing Market

The Single-use Bioprocessing market is segmented based on type and application. Each segment offers unique insights into the market’s development and growth potential. Types include pH sensors, valves, bench-top control systems, and spectroscopy, all of which play critical roles in maintaining process consistency and ensuring high-quality biopharmaceutical production. By application, the market is divided into the biotechnology industry, pharmaceutical industry, and academic research, with biotechnology and pharmaceutical sectors leading the demand. Academic institutions also contribute significantly to market growth due to increased investments in research and development, driving technological advancements in bioprocessing systems.

By Type

• pH Sensors: pH sensors are a fundamental component of the Single-use Bioprocessing market, responsible for monitoring and controlling pH levels during production processes. These sensors are widely used in biotechnology and pharmaceutical industries to ensure the stability and effectiveness of biologic products. The global demand for pH sensors has been increasing as more industries shift to single-use systems, providing enhanced monitoring capabilities. Approximately 35% of the total market share is attributed to pH sensors due to their importance in maintaining optimal conditions for cell culture and fermentation processes.

• Valves: Valves are essential in single-use bioprocessing systems, controlling the flow of fluids and gases during production. They are critical in ensuring precise and sterile handling of materials. Valves account for nearly 25% of the market share, driven by their need in areas such as bioreactor systems, filtration systems, and chromatography. Single-use valves provide advantages over traditional systems by reducing contamination risks and the need for sterilization. As the pharmaceutical industry scales up production, the use of single-use valves has seen significant growth, particularly in the production of vaccines and monoclonal antibodies.

•  Bench-top Control Systems: Bench-top control systems are gaining prominence in the Single-use Bioprocessing market due to their user-friendly interface and ability to monitor multiple variables in real-time. These systems are particularly useful in small-scale operations or pilot studies within the biotechnology and pharmaceutical industries. They account for around 20% of the market share, with an increasing demand for real-time data analysis and process optimization. The ease of use and flexibility offered by bench-top systems make them a preferred choice for academic research and small-scale productions, contributing to their rising adoption.

• Spectroscopy: Spectroscopy is increasingly utilized for process analysis in single-use bioprocessing, helping manufacturers identify and quantify critical parameters such as protein concentration, cell density, and glucose levels. Spectroscopy holds a smaller market share, contributing about 10%, but is gaining traction in the biotechnology sector, especially in applications where precise measurements are required. The technology allows for efficient inline analysis and monitoring, reducing the need for off-line testing, making it valuable in high-throughput environments where time and accuracy are critical.

By Application

• Biotechnology Industry: The biotechnology industry leads the Single-use Bioprocessing market due to its significant reliance on biologics and cell-based therapies. The sector’s rapid expansion, driven by the demand for innovative treatments, is expected to contribute around 40% of the market share. Single-use bioprocessing systems offer the scalability and flexibility necessary for biopharmaceutical production, from research to commercialization. These systems are widely used in vaccine production, monoclonal antibody manufacturing, and gene therapy applications, where maintaining sterility and optimizing efficiency are paramount.

• Pharmaceutical Industry: The pharmaceutical industry holds the second-largest market share, accounting for nearly 35% of the total market. The industry's demand for single-use bioprocessing systems is driven by the need for efficient and cost-effective manufacturing solutions for large-scale drug production. These systems are used to streamline biomanufacturing processes and ensure the high purity of pharmaceutical products. In particular, the production of vaccines and biologic drugs is a major contributor to the growth in this segment. Pharmaceutical companies are investing in single-use technologies to enhance productivity and reduce production downtime.

• Academic Research: Academic research institutions are increasingly adopting single-use bioprocessing systems to enhance their research capabilities. This segment contributes approximately 25% of the market share, driven by the growing need for high-quality, reproducible results in cellular and molecular biology research. Single-use systems offer academic researchers an affordable and efficient way to conduct experiments and trials, providing flexible, scalable solutions for experimental research in areas like gene therapy, cancer research, and regenerative medicine. Their ease of use and reduced risk of contamination make them ideal for academic environments.

Regional Outlook

The Single-use Bioprocessing market has a global presence, with key regions contributing to its growth. North America, Europe, Asia-Pacific, and the Middle East & Africa have seen notable investments in single-use technologies, driven by the increasing demand for biologics, pharmaceuticals, and biotechnological advancements. North America leads the market in adoption, with Europe and Asia-Pacific following closely. The Middle East & Africa, while smaller in comparison, are projected to see significant growth due to expanding healthcare infrastructure and biopharmaceutical manufacturing capabilities.

North America

North America holds the largest market share, accounting for around 40% of the global Single-use Bioprocessing market. The region’s dominance is primarily due to the established pharmaceutical and biotechnology sectors in the U.S. and Canada, where companies are increasingly adopting single-use systems to enhance production efficiency. The growing focus on biologics and the rise of cell and gene therapies have further accelerated the demand for single-use technologies. Investments in R&D and the increasing number of biologics being produced in North America continue to drive market expansion in this region.

Europe

Europe accounts for approximately 30% of the Single-use Bioprocessing market share. The European market is primarily driven by the presence of large pharmaceutical and biotechnology companies, particularly in countries such as Germany, the UK, and Switzerland. The region is also seeing increased demand for personalized medicine and biologic drug production, leading to a higher adoption rate of single-use technologies. Europe’s strict regulatory standards for the pharmaceutical industry further reinforce the demand for single-use bioprocessing systems, ensuring the quality and safety of biologics produced within the region.

Asia-Pacific

Asia-Pacific represents a rapidly growing market for Single-use Bioprocessing systems, contributing about 20% to the global market share. The region is experiencing a surge in pharmaceutical manufacturing, particularly in China and India, which are increasingly adopting single-use systems to boost production capabilities. The rise in biologic drug demand, coupled with the growth of biotech startups and R&D facilities in countries like Japan and South Korea, is expected to fuel further expansion. Moreover, Asia-Pacific’s cost-effective manufacturing processes make it an attractive region for global biopharma companies.

Middle East & Africa

The Middle East & Africa region accounts for approximately 10% of the global Single-use Bioprocessing market share. The region is seeing growing investments in pharmaceutical manufacturing and healthcare infrastructure, with countries like the UAE and Saudi Arabia leading the charge. While smaller compared to other regions, the demand for single-use systems in biopharmaceutical production is rising, driven by the increasing focus on healthcare and biotechnology advancements. These developments are expected to foster market growth in the Middle East & Africa, particularly in the context of expanding manufacturing capacities and research initiatives.

Key Players in the Single-use Bioprocessing Market

• Thermo Fisher Scientific, Inc.
• Sartorius AG
• Merck KGaA
• Danaher Corporation
• GE Healthcare
• Pall Corporation
• Eppendorf AG
• Bio-Rad Laboratories, Inc.
• Saint-Gobain Life Sciences
• 3M Company
• Fujifilm Corporation
• Lonza Group
• MilliporeSigma
• Becton, Dickinson and Company (BD)
• Corning Incorporate

Top Companies in the Single-use Bioprocessing Market with Highest Share

• Thermo Fisher Scientific, Inc.: Thermo Fisher is one of the top players in the single-use bioprocessing market, holding a significant share due to its diverse product range and strong presence in biotechnology, pharmaceutical, and research industries. The company’s offerings, such as single-use sensors and filtration systems, make it a key player in bioprocessing solutions. The company's recent acquisitions and collaborations further enhance its market position.

• Sartorius AG: Sartorius AG, a leading global supplier of laboratory and process technologies, holds a major market share in the single-use bioprocessing market. The company’s products, such as single-use bioreactors and filtration devices, are highly valued in both pharmaceutical and biotechnology sectors. Sartorius has strengthened its position through strategic partnerships and investments in advanced technologies, positioning itself as a market leader.

Investment Analysis and Opportunities

The single-use bioprocessing market presents ample investment opportunities, driven by the increasing demand for efficient and cost-effective manufacturing solutions in biopharmaceutical production. Investment in research and development (R&D) is key for companies seeking to expand their portfolios and improve product quality. Companies investing in innovation, particularly those focusing on automation and digital technologies, are expected to lead in the long run. With the pharmaceutical industry continuing to grow, there is a rising need for cost-efficient bioprocessing systems that reduce time-to-market. The growing focus on personalized medicine also offers a significant opportunity for market players to develop advanced solutions tailored to specific needs. Moreover, expanding presence in emerging markets, particularly in Asia-Pacific, is an attractive investment opportunity for market players aiming for long-term growth. Market players can also benefit from forging strategic partnerships and collaborations with academic institutions and research organizations to improve product development.

New Products Development

Product innovation is crucial for maintaining a competitive edge in the single-use bioprocessing market. Companies are constantly developing new and improved products to address the evolving needs of the biotechnology and pharmaceutical industries. In 2023 and 2024, several market leaders introduced new products to enhance process efficiencies, improve product yields, and ensure compliance with regulatory standards. For instance, Thermo Fisher Scientific introduced new sensor technologies designed to enhance the monitoring of bioprocesses, while Sartorius AG unveiled a range of advanced single-use bioreactors. Other notable developments include the launch of smart valves and sensors that offer real-time monitoring and control capabilities, making the bioprocessing systems more intelligent and automated. These product innovations allow manufacturers to minimize human error, reduce contamination risks, and ensure better scalability of bioprocessing solutions, which in turn improves product quality and cost-efficiency. As market demands grow for more precise and rapid biomanufacturing solutions, product development in this sector will remain a key driver of market growth.

Recent Developments by Manufacturers in the Single-use Bioprocessing Market

• Thermo Fisher Scientific launched a new line of disposable cell culture media that enhances the bioprocessing workflow by offering higher yields and reducing the risk of contamination.
• Sartorius AG introduced an advanced single-use bioreactor designed to increase scalability and reduce operational costs for large-scale manufacturing in biopharmaceutical production.
• Merck KGaA unveiled a new line of pH sensors with improved accuracy and long-term reliability, ensuring more precise monitoring in bioprocessing applications.
• GE Healthcare enhanced its single-use filtration systems by incorporating advanced monitoring tools for better real-time control of bioprocessing steps, boosting product consistency.
• Lonza Group launched a next-generation valve system for single-use bioreactors that improves system integration and minimizes operational downtime, improving overall efficiency.

Report Coverage of the Single-use Bioprocessing Market

The report on the single-use bioprocessing market provides an in-depth analysis of key market drivers, restraints, opportunities, and challenges. It offers insights into market dynamics, including detailed segmentation by type (e.g., pH sensor, valve, bench top control system, spectroscopy) and application (e.g., biotechnology, pharmaceutical, academic research). The report also highlights regional insights, with an emphasis on North America, Europe, Asia-Pacific, and the Middle East & Africa. It further covers key players in the market, their strategies, and recent product developments. This comprehensive analysis is designed to assist stakeholders in making informed decisions by providing data-driven forecasts, technological trends, and the competitive landscape of the single-use bioprocessing market from 2025 to 2033.